ePoster listing and sessions

Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London

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Diffusion Restriction in patients with IgG4 related orbital disease

Author: Tahmina Nazari
ePoster Number: 116


On magnetic resonance imaging (MRI), diffusion weighed imaging (DWI) and apparent diffusion coefficient (ADC) can be used to determine diffusion restriction (DR). DR is widely used to differentiate between orbital lymphoma (OL) and (idiopathic) orbital inflammation (IOI). A subtype of IOI patients has IgG4 related orbital disease (IgG4ROD). In this study, the presence or absence of diffusion restriction (DR) in patients with IgG4ROD was investigated.


In this retrospective study, the MRI images of 20 patients with biopsy proven IgG4ROD were studied. Special attention was paid to the DWI and ADC sequences, on the basis of which the presence or absence of DR was determined. The number of IgG4ROD patients with DR was determined and compared to the literature concerning DR in orbital disease.


A considerable amount of patients with IgG4ROD showed DR. In the literature no reports on this specific subject have been made to our knowledge.


Presence of diffusion restriction in patients with an orbital mass does not reliably differentiate between orbital lymphoma and IgG4 related orbital disease.

Additional Authors

First nameLast nameBase Hospital / Institution
RachelKalmannUMC Utrecht
Willemiende BruijnUMC Utrecht
OzlemEnginUMC Utrecht

Abstract ID: 21-159