ePoster listing and sessions

Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London

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ORBITAL MASSES – A SINGLE-CENTER RETROSPECTIVE REVIEW

Author: Raquel Félix
ePoster Number: 281


Purpose

Orbital masses remain a challenging diagnosis, despite meticulous evaluation. Frequently surgery is required for diagnostic or curative purposes. In this study we aim to review the epidemiology, clinical presentation and definitive diagnosis of operated orbital masses in our centre.


Methods

Retrospective, non-comparative, consecutive series of patients referred for orbital mass, undergoing surgery (including incisional biopsy) in the Ophthalmology Department of Centro Hospitalar Universitário de Coimbra, over an 8-year period (2013-2021). Presumptive diagnosis was based on clinical and imaging findings. Definite diagnosis was obtained by histopathology.


Results

The study included 49 eyes of 49 patients, with a mean age of 62.8±14.5 years (range 33-93), 63.3% of which were female. Symptoms were present for 10.3±10.7 months at presentation. The most frequent sign or symptom was a palpable mass in 55.1%, followed by proptosis in 46.9% and palpebral edema in 32.7%. Orbital computed tomography was done on 95.9% of cases, with 55.1% also being evaluated by magnetic resonance imaging. Lesions were exclusively extraconal in 55.1% of cases, exclusively intraconal in 32.7%, and affected both compartments in 12.2%. The superior temporal quadrant was most frequently involved (38.8%). In 65.3% of patients only incisional biopsy was done. Malignant etiology was found in 65.3%, including 18 lymphoproliferative tumours (11 MALT lymphomas). There were 5 cases of orbital metastases, 3 from breast cancer. Patients with malignancy were significantly older (66.5±14.2 vs 55.8±12.7 years, p=0.031). Symptom duration at presentation was inferior in the malignant group, however with no statistical significance (8.9±9.7 vs 12.7±12.5 months, p=0.236).


Conclusion

Our results show a high proportion of malignant masses, though biased by the need of surgical intervention/diagnosis in such cases. A palpable mass and proptosis were the most frequently encountered clinical signs and lesions mostly affected the extraconal space and the superior temporal quadrant. Patients with malignant disease were significantly older.


Additional Authors

First nameLast nameBase Hospital / Institution
JoanaProvidênciaCentro Hospitalar Universitário de Coimbra
MiguelRaimundoCentro Hospitalar Universitário de Coimbra
FilipaPoncesCentro Hospitalar Universitário de Coimbra
GuilhermeCastelaCentro Hospitalar Universitário de Coimbra

Abstract ID: 21-188