ePoster listing and sessions

Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London

 

 

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Glucocorticoids in the treatment of non-infectious superior ophthalmic vein thrombosis

Author: Samuel Sigurdsson
ePoster Number: 132


Purpose

To describe three cases of superior ophthalmic vein thrombosis successfully treated with glucocorticoids after treatment failure with conventional therapy.

Superior ophthalmic vein thrombosis (SOVT) is a rare clinical entity, which can have a septic and an aseptic cause. Aseptic SOVT is normally treated with anticoagulation and glucocorticoids are withheld unless there is concurrent orbital inflammation.


Methods

The study was performed in accordance with Helsinki Declaration. Informed written consent was obtained from patients for being included in the study.


Results

We describe three patients, who all presented with various degrees of proptosis, ophthalmoplegia, orbital stasis and reduced vision. One patient was confirmed to have isolated superior ophthalmic vein thrombosis, while the other two patients had concurring cavernous sinus thrombosis. All patients had an underlying carotid-cavernous fistula with no signs of infection. The patients were initially treated with parenteral anticoagulation, two patients were given intraocular pressure reducing medication, one of whom underwent canthotomy-cantholysis. During anti-coagulation treatment, two patients experienced gradual worsening of symptoms and signs and one patient improved before deterioration. All patients received additional treatment with glucocorticoids consisting of a three-day treatment with intravenous methylprednisolone 500 mg, followed by oral glucocorticoids resulting in total regression of symptoms. Two patients regained 20/20 vision, with some vision field defects, while the third patient regained 20/25 vision.


Conclusion

The addition of glucocorticoids in the treatment of aseptic superior ophthalmic vein thrombosis can lead to improvement of symptoms and a potentially better prognosis.


Additional Authors

First nameLast nameBase Hospital / Institution
ElinBohman1St. Erik Eye Hospital, Stockholm, Sweden. 2Division of Eye and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
FrankTräisk1St. Erik Eye Hospital, Stockholm, Sweden. 2Division of Eye and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
UrszulaArnljots1St. Erik Eye Hospital, Stockholm, Sweden. 2Division of Eye and Vision, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Abstract ID: 21-196