Abstract Listings 2024

Semi-Automated MRI-Based Method for Orbital Volume and Contour Analysis

Author: Daphna Landau
Base Hospital / Institution: Sheba Medical Center

Rapid fire oral presentation

Abstract ID: 24-147

Purpose

The architecture of the orbital cavity is intricate, and precise measurement of its growth is essential for managing ocular and orbital pathologies. Most methods for those measurements are by computerized tomographic (CT) imaging, although magnetic resonance imaging (MRI) for soft tissue assessment is indicated in many cases, specifically pediatric patients. This study introduces a novel semi-automated MRI-based approach for depicting orbital shape and dimensions.


Methods

A retrospective cohort study including patients with at least one normal orbit who underwent both CT and MRI imaging at a single center from 2015 to 2023. Orbital dimensions included volume, horizontal and vertical lengths, and depth. These were determined by manual segmentation followed by 3-dimensional (3D) image processing software. Main outcome measures were differences in orbital measurements between MRI and CT scans.


Results

Thirty-one patients (mean age 47.7±23.8 years, 21 [67.7%]) females, were included.
The mean differences in delta values between orbital measurements on CT vs. MRI were: volume 0.03±2.01 ml, horizontal length 0.53±2.12 mm, vertical length, 0.36±2.53 mm, and depth 0.97±3.90 mm. The CT and. MRI orbital measurements were strongly correlated: volume (r=0.92, P<0.001), horizontal length (r=0.65, P<0.001), vertical length (r=0.57, P=0.001), and depth (r=0.46, P=0.009). The mean values of all measurements were similar on the paired-samples t-test: P=0.9 for volume (30.86±5.04 ml on CT and 30.88±4.92 ml on MRI), P=0.2 for horizontal length, P=0.4 for vertical length, and P=0.2 for depth.


Conclusion

We present an innovative semi-automated method capable of calculating orbital volume and demonstrating orbital contour by MRI validated against the gold standard CT-based measurements. This method can serve as a valuable tool for evaluating diverse orbital processes.


Additional Authors

First name Last name Base Hospital / Institution
Lital Smadar Sheba Medical Center
Mattan Arazi Sheba Medical Center
Gahl Greenberg Sheba Medical Center
Limor Haviv Sheba Medical Center
Or Benifla Sheba Medical Center
Mayan Dagan Sheba Medical Center
Joel M. Gutovitz Sheba Medical Center
Guy Ben Simon Sheba Medical Center

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