Semi-Automated MRI-Based Method for Orbital Volume and Contour Analysis
Author: Daphna Landau
Base Hospital / Institution: Sheba Medical Center
Rapid fire oral presentation
Abstract ID: 24-147
Purpose
The architecture of the orbital cavity is intricate, and precise measurement of its growth is essential for managing ocular and orbital pathologies. Most methods for those measurements are by computerized tomographic (CT) imaging, although magnetic resonance imaging (MRI) for soft tissue assessment is indicated in many cases, specifically pediatric patients. This study introduces a novel semi-automated MRI-based approach for depicting orbital shape and dimensions.
Methods
A retrospective cohort study including patients with at least one normal orbit who underwent both CT and MRI imaging at a single center from 2015 to 2023. Orbital dimensions included volume, horizontal and vertical lengths, and depth. These were determined by manual segmentation followed by 3-dimensional (3D) image processing software. Main outcome measures were differences in orbital measurements between MRI and CT scans.
Results
Thirty-one patients (mean age 47.7±23.8 years, 21 [67.7%]) females, were included.
The mean differences in delta values between orbital measurements on CT vs. MRI were: volume 0.03±2.01 ml, horizontal length 0.53±2.12 mm, vertical length, 0.36±2.53 mm, and depth 0.97±3.90 mm. The CT and. MRI orbital measurements were strongly correlated: volume (r=0.92, P<0.001), horizontal length (r=0.65, P<0.001), vertical length (r=0.57, P=0.001), and depth (r=0.46, P=0.009). The mean values of all measurements were similar on the paired-samples t-test: P=0.9 for volume (30.86±5.04 ml on CT and 30.88±4.92 ml on MRI), P=0.2 for horizontal length, P=0.4 for vertical length, and P=0.2 for depth.
Conclusion
We present an innovative semi-automated method capable of calculating orbital volume and demonstrating orbital contour by MRI validated against the gold standard CT-based measurements. This method can serve as a valuable tool for evaluating diverse orbital processes.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Lital | Smadar | Sheba Medical Center |
| Mattan | Arazi | Sheba Medical Center |
| Gahl | Greenberg | Sheba Medical Center |
| Limor | Haviv | Sheba Medical Center |
| Or | Benifla | Sheba Medical Center |
| Mayan | Dagan | Sheba Medical Center |
| Joel M. | Gutovitz | Sheba Medical Center |
| Guy | Ben Simon | Sheba Medical Center |