Abstract Listings 2024

Morphological changes after treating anophthalmic socket syndrome

Author: TOSHIKI NISHIZUMI
Base Hospital / Institution: Oculofacial Clinic Group

ePoster presentation

Abstract ID: 24-215

Purpose

Anophthalmic socket syndrome (ASS) is characterized by the hallmark feature of superior sulcus depression, upper eyelid ptosis, and lower eyelid laxity. Facial asymmetry owing to ASS leads to psychological disturbance to decrease patient’s quality of life, however, quantitative analysis is not well documented. This study aimed to analyze the detail of psychological and eyelid changes by treating ASS.The study involved consecutive 21 patients (6 males and 15 females) with ASS, mean age of 52.6±16.8 who underwent anophthalmic reconstruction with revision of orbital implantation and customized eyelid surgery in our institution.


Methods

Image-J Fiji was used to measure various eyelid parameters including Margin Reflex/Prosthesis Distance (MRD)-1 and 2, Central Pupil/Prosthesis-to-Brow Height (CPBH), and area of upper eyelid sulcus defined as the area of shadow, before and after surgery. The healthy eyelid set as a control to compare the parameters pre- and post-operatively, using the Wilcoxon signed-rank test.


Results

MRD-1 ratio to the healthy side improved from 0.63 to 0.92(p=0.02), while MRD-2 ratio didn’t show dramatically improvement. CPBH ratio to the healthy side decreased from 1.19 to 1.03 (p=0.02). The ratio of shadow area was changed dramatically from 5.14 to 2.87 (p=0.01). Although the postoperative average ratio was 2.87, 6 cases showed their ratio around 1 (0.73~1.29).


Conclusion

The surgeries for ASS improved all eyelid parameters except for MRD-2. Especially, adequate anophthalmic reconstruction and eyelid surgeries may improve CPBH and sunken eye area dramatically. As previous reports mentioned that ASS leads to poor psychological outcomes and we demonstrated effectiveness of treatment.. This study didn’t evaluate enough psychological changes in patients with ASS before and after treatment using scoring due to lack of numbers. So future studies should further refine treatment approaches and optimize outcomes for patients with ASS. Although image-processing analysis is still challenging, it is important to assess treatment effects more objectively.


Additional Authors

First name Last name Base Hospital / Institution
TOMOYUKI KASHIMA Oculofacial Clinic Group
NATSUYO YOSHIDA-HATA Oculofacial Clinic Group

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