Anopthalmic Socket Complications in Retinoblastoma Patients
Author: Reham AlQahtani
Base Hospital / Institution: King Khalid Eye Specialist Hospital
ePoster presentation
Abstract ID: 24-250
Purpose
To identify the complications of anophthalmic socket in retinoblastoma patients either structural or aesthetic
Methods
The study follows a retrospective case series design of the long-term (40 years) outcomes of acquired anophthalmic socket in retinoblastoma patients at a tertiary eye care, Riyadh, Saudi Arabia.
Results
A total of 451 eyes of 436 persons were recruited in the current study, where 209 (48%) were male and 227 (52%) were female. Meanwhile, hereditary was present in 26 (5.8%) of cases.Other tumors were identified in 28 (6.2%) of cases. Moreover, adjuvant therapy was found in 257 (57%) and 194 (43%) has no adjuvant therapy.During postoperative follow-up assessment, 60 (13.3%) of cases had one or more postoperative complications. The majority of these complications were contracted socket 26 (5.8%), followed by implant exposure 13 (2.9%). There was a statistically significant association between encountering a contracted socket and cryotherapy (p=0.013), while there was a highly significant association between the contracted socket and the application of radiotherapy (p<0.0001).
Moreover, periocular changes happened in five (1.1%) cases, where Lash loss was detected in 2 (0.4%) cases, while both leiomyosarcoma and orbital bone hypoplasia were found in only one case each (0.2%). In terms of radiotherapy, there is also a statistically significant association between Leiomyosarcoma, Orbital bone hypoplasia, and NLDO with radiotherapy modality (p-value = 0.018). Ptosis was found in 42 (9.3%), and the MMG was the most needed surgery, 15 (3.3%) while Levator resection, 14 (3.1%) was the highest needed eyelid surgery.
Conclusion
Eneculation is quite common in retinoblastoma patients with anophthalmic socket. Though different successful treatment modalities are available, the frequency of postoperative complications is still relatively high. The selection of the most proper intervention should be evaluated in the light of other associated risk factors to minimize such potential complications.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Hailah | Alhussain | King Khalid Eye Specialist Hospital |
| Khawlah | Alzeban | King Khalid Eye Specialist Hospital |
| Ashwaq | Asseri | King Khalid University |
| Mohammed | AlShehri | King Khalid Eye Specialist Hospital |
| Ahmed | Mosa | King Khalid Eye Specialist Hospital |
