Orbital and periorbital tumours and orbital exenteration 2005-2022: our experience in Finland
Author: Paula Niinimäki
Base Hospital / Institution: Helsinki University Eye Hospital
ePoster presentation
Abstract ID: 24-301
Purpose
To evaluate the indications of orbital exenteration, possible delays, ophthalmic status, challenges, management, and prognosis of patients treated by orbital exenteration in a tertiary care centre.
Methods
Patients who underwent orbital exenteration were identified from the Helsinki University Hospital databases during an 18-year period (2005-2022). Age, sex, primary location of the tumour, histopathologic diagnosis, preoperative treatments, status of surgical margins, presence of metastatic disease, and postoperative survival were retrieved.
Results
Altogether 69 patients were exenterated during the study period. The median (md) age was 74 years (range, 7–93), 54% were men. All but one case was performed because of malignant tumour. Origins of the tumours were skin in 21 (30%), conjunctiva in 11 (16%), intraocular in 10 (15%) and maxillary sinus in 10 patients (15%). Histopathological diagnosis was uveal melanoma in ten (13%), BCC in nine (13%), cutaneous SCC in eight (12%) and conjunctival melanoma and maxillary sinus SCC both in six (9%) patients. 39 patients (58%) were treated previously. The md follow-up time was 16 (range 0–169) months. Three patients (4%) died from immediate complications of the operation. Three patients (4%) developed a local recurrence md of 16 (range 2-63), 14 patients (20%) metastatic disease md 14 months (range 3-163 months), both local and metastatic disease six patients (9%) md 13 months (range 4-59) and 23 patients (33%) died of metastatic disease md 10 (range 0-168) months after the orbital exenteration. Seven of those who died from the disease had local, 16 patients had spread disease at the time of the exenteration.
Conclusion
It should pay attention to surgical margins and histopathological risk factors in primary operations to avoid ending to exenteration. The orbital exenteration team should select noticing location and histology of the tumour and choose the correct surgical and reconstruction technique, preceding multiplicinary planning and an ophthalmologist’s examination to face the loss of the patient’s eye.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Maria | Määttänen | Helsinki University Eye Hospital |
| Jyrki | Vuola | Helsinki University Eye Hospital |
| Tero | Kivelä | Helsinki University Eye Hospital |
| Antti Mäkitie | Helsinki University Eye Hospital | |
| Marita | Uusitalo | Helsinki University Eye Hospital |
