Changes in Intraocular Pressure following Eyelid Ptosis Repair
Author: Katherine Lucarelli
Base Hospital / Institution: University of California, Los Angeles
ePoster presentation
Abstract ID: 24-307
Purpose
Eyelid surgery has not been shown to have a significant effect on intraocular pressure (IOP) in the three to six month postoperative period. The authors conducted a prospective nonrandomized intervention study to evaluate the effect of anterior and posterior blepharoptosis surgery on short term postoperative IOP.
Methods
Patients with no previous ocular history were assigned to receive external levator resection (ELR) or müller muscle conjunctival resection (MMCR) based on ptosis severity and response to the phenylephrine test. Averaged IOP measurements were obtained at three time points: one week preoperative, one week postoperative and six weeks postoperative. Goldmann applanation was performed below the corneal center to avoid lifting the eyelid, and readings were taken in the afternoon hours to mitigate diurnal variations. Linear mixed-effects modeling was utilized to assess the changes in IOP with age and sex included as covariates. All analysis was performed using R software (version 4.4.0).
Results
Thirty-nine patients were included in the study. Twenty-four patients received ELR. Fifteen patients received MMCR. The main effect of time was significant for postoperative week one, with an increase in IOP compared to baseline (β = 1.79, p < 0.001). However, the change in IOP at week six compared to baseline was not statistically significant (β = 0.54, p = 0.182). The main effect of surgical group (MMCR vs ELR) on IOP was not significant (p=0.461). The interaction terms between treatment group and time were also not statistically significant at week one 1 (p=0.673) nor at week six (p=0.482). Additionally, neither age nor sex had a significant influence on IOP (p=0.614, p=0.163, respectively).
Conclusion
While there was a significant increase in IOP at initial follow-up 1-week post-operatively compared to baseline, this increase did not differ between the MMCR and ELR groups, and there was no significant change at follow-up 6-weeks postoperatively compared to baseline.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Ashley | Shirriff | University of California, Los Angeles |
| Cynthia | Boxrud | University of California, Los Angeles |
