Abstract Listings 2024

Purpose

This study aims to evaluate the changes in volume and thickness of filler material as observed through MRI scans and to assess the effects of Hyalase injections on these parameters.

Methods

A case series of seven patients who underwent filler injections was analyzed. Each patient had 2 to 3 MRI scans taken at different intervals to monitor the filler material.
Following initial observations, Hyalase was injected into specific filler sites, and subsequent MRI scans were obtained. Changes in filler volume and thickness were measured and compared across different time points pre- and post-Hyalase injection.

Results

Hyalase significantly reduced the filler volume and thickness in certain patients. Notably, areas that were not treated with Hyalase showed no change in thickness, indicating the localized effectiveness of the treatment. In one patient, a natural reduction in volume over time was observed, suggesting that filler degradation can occur without intervention, albeit at a slower rate. Conversely, another patient exhibited an unexpected expansion in volume without any additional filler injections, highlighting the variability in filler behavior over time. These findings underscore the efficacy of Hyalase in targeted filler reduction and the necessity for ongoing monitoring of untreated areas to understand the full spectrum of filler dynamics.

Conclusion

The study demonstrates that MRI is a valuable tool for monitoring the behavior of filler materials in vivo. The observed reduction in filler volume and thickness over time aligns with expected degradation patterns. Hyalase injections significantly accelerate this process, providing a reliable method for correcting overfilled or misplaced filler material. These findings support the use of MRI and Hyalase as effective tools in the management and correction of aesthetic filler procedures.

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