Surgical treatment in Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome: A Retrospective Single-Center Study
Author: Medea Ettl
Base Hospital / Institution: LMU eye clinic Munich
ePoster presentation
Abstract ID: 24-373
Purpose
Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome (BPES) is a rare condition usually treated at specialized eye clinics only. Surgical therapy addresses correction of ptosis, epicanthus, and telecanthus.
Methods
All patients diagnosed with BPES at the LMU Eye Department in the period 1994 to 2023 were included in this retrospective study. Analyzed data included oculoplastic examinations, surgical reports, orthoptic evaluations, and genetic analyses.
Results
In total, 150 patients were clinically diagnosed with BPES, of which 99 patients underwent surgical corrective treatments at the LMU Eye Department. However, due to data loss after digitalization of patients’ files and exclusion of patients with aberrant BPES or prior surgery in another institution, only 55 patients (50.9% (28) female / 49.1% (27) male) remained eligible for further analysis. The median follow-up period was 17.1 (0.1-242.4) months. The performed interventions comprised Y-V plasty only 3.6% (2), frontalis suspension only 41% (23), Y-V plasty and suspension 49% (27), and Y-V plasty and anterior levator resection (ALR) 5.4% (3). Complications after frontalis suspension: 8% (4) thread dehiscence, 12% (6) thread granulomas, 4% (2) lid infections. Complications following Y-V plasty: 10.3% (3) granulomas, 3.4% (1) wound healing disorders, 6.9% (2) bleedings, 10% (3) infections. Re-frontalis suspensions were performed due to ptosis recurrence 6% (3), thread dehiscence 8% (4) or thread granuloma 6% (3). Thread granulomas were removed in 10% (5). Overall, 70.1% (39) of the patients reported satisfaction with the surgical outcome, 26.3% (14) could not be surveyed due to missing information on patient satisfaction, and only 3.6% (2) were dissatisfied.
Conclusion
In our hands, surgical correction of BPES including frontalis suspension and Y-V plasty show good results, matching patients’ realistic aesthetic expectations in the majority of cases. Only manageable complications were observed.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Prof. Dr. Christoph | Hintschich | LMU eye clinic Munich |
| Dr. Anna | Schuh | LMU eye clinic Munich |
