Abstract Listings 2025

Purpose

To describe a rare postoperative complication in a patient with Xeroderma Pigmentosum (XP), emphasizing the role of eyelid integrity in ocular surface maintenance.

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Methods

A case report.

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Results

A 35-year-old man with genetically confirmed XP with a history of surgical excision of a malignant tumor from the left lower eyelid. Ophthalmological examination revealed a suspicious pigmented lesion on the right lower lid, bilateral ectropion, conjunctival hyperemia, right inferior corneal conjunctivalization, and cicatricial adhesion between the tarsal conjunctiva and cornea in the left eye consistent with a ”Keratoblepharon”. This adhesion led to restricted ocular motility, lagophthalmos with exposure keratopathy, and focal corneal opacification. Management included surgical lysis of adhesions followed by ocular surface rehabilitation.

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Conclusion

This case highlights the vulnerability of the ocular surface following structural disruption of the eyelid, particularly in XP, where epithelial fragility and poor healing predispose to cicatricial complications. Keratoblepharon, although rare, underscores the functional link between eyelid anatomy and corneal protection. Prevention requires careful perioperative planning and tissue-preserving techniques to safeguard long-term ocular surface integrity.

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Additional Authors

First name	Last name	Base Hospital / Institution
Mohamed	Ghachem	Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia
Iheb	Elouati	Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia
Oumayma	Chourabi	Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia
Leila	Knani	Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia
Mohamed	Ghorbel	Department of Ophthalmology, Farhat Hached University Hospital, Sousse, Tunisia

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