A rare primary eyelid carcinoma –mucinous
Author: Ahmed Shalid
Base Hospital / Institution: Hull University Teaching Hospitals
ePoster presentation
Abstract ID: 25-514
Purpose
Mucinous adenocarcinoma is a rare cancer of the mucin cells with a prevalence of 0.4 in 1000,000. What is even rarer is its presentation as a primary lid lesion. This is a case presentation of a patient presenting to our local eye unit with 1 year history of a left lower eyelid mass that had gradually increased in size.
Methods
On presentation the patient had a 5x4mm telangiectatic elevated nodule with an area of mixed haemorrhage and madarosis which was sent for incisional biopsy.
Results
Histology showed a dermal tumour of cuboidal cells with eosinophilia cytoplasm surrounded by mucinous stroma. Focal apocrine decapitation type of secretion was also noted. Immunohistochemistry showed positive CK7, GATA3 and GCDP. Negative CK20, chromogranin and synaptophysin.
The patient also underwent a systemic work up including:
PET-CT scan that showed no distant metastasis and required no systemic treatment
The patient underwent frozen section excision and lid reconstruction
Conclusion
Eyelid mucinous carcinoma represents 1% of cutaneous primary mucinous carcinoma, and must be considered as a differential for BCC
Risk of metastasis is reported at 5-10% with regional lymph nodes or distant organs like the lungs or liver
Systemic work-up is key to ensure no distance metastasis or non-primary origin given lower prevalence of primary eyelid presentation
Consideration of incisional biopsy in atypical featured lid masses
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Zeyad | Al-Moasseb | Hull University Teaching Hospitals |
| Yahya | Khedr | Hull University Teaching Hospitals |
| Egle | Rostron | Hull University Teaching Hospitals |
| Sreedhar | Jyothi | Hull University Teaching Hospitals |
| Colin | Vize | Hull University Teaching Hospitals |
