Management of periocular basal cell carcinoma by Mohs micrographic surgery: a ten-year retrospective analysis of outcomes.
Author: Robert Thomas Brady
Base Hospital / Institution: Addenbrooke’s Hospital, Cambridge
Rapid fire oral presentation
Abstract ID: 25-548
Purpose
Retrospective interventional case series covering ten years of practice.To determine the success of Mohs micrographic surgery (MMS) for periocular basal cell carcinoma (BCC) at Addenbrooke’s Hospital, a tertiary referral centre in Cambridge, England.
Methods
Review of medical records of 664 consecutive patients who underwent MMS for confirmed periocular BCC. The main outcome measure was biopsy-proven recurrence of BCC at the same anatomical location after MMS. Secondary outcome measures included tumour site, histological subtype and length of follow-up. Results were compared with a previous 5-year audit (Jan 2003 to July 2008).
Results
664 patients were identified as having undergone MMS for periocular BCC from October 2014 to March 2024. 658 (99%) of the surgeries were for primary BCC and 6 procedures (1%) were for recurrent or residual BCC. Three patients (0.5%) were identified as having Gorlin Syndrome and were excluded from the analysis. The mean follow-up was 28 months (range 1-85 months). Five recurrences were identified in total. The recurrence rate following MMS for primary BCC was 0.76% (5 patients) which is lower than the rate determined during the previous audit at 1.6% for those undergoing primary excision of tumours. The mean time to recurrence was 44 months (range 15- 144). There was a significant drop in patients undergoing Mohs for previous WLE and a large increase in patient numbers when compared to the previous audit (104 versus 664 patients)
Conclusion
MMS for primary BCC has a very high success rate for complete excision without recurrence. Additionally, we have found a reduction in recurrence in comparison to a previous audit in spite of a 300% increase in patients undergoing Mohs micrographic surgery in this time period.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Mei Ken | Low | Addenbrooke’s Hospital, Cambridge, UK |
| Simon | Woodruff | Addenbrooke’s Hospital, Cambridge, UK |
| Cornelius | René | Addenbrooke’s Hospital, Cambridge, UK |
