Correlation Between Corneal Morphological Alterations in Congenital Vs Acquired Ptosis Using MS39 anterior segment OCT and topographer
Author: Ichrek Benouaa
Base Hospital / Institution: excellence clinique ophtalmologique
Rapid fire oral presentation
Abstract ID: 25-278
Purpose
To evaluate the correlation between congenital or acquired ptosis and corneal morphological changes, focusing on both quantitative and qualitative tomographic alterations. Assessments were performed using the MS39 tomographer, with emphasis on topographic indices suggestive of keratoconus and irregular astigmatism
Methods
A prospective observational study was conducted at Excellence Clinique Ophtalmologique, Algiers between august 2024 and march 2025. The study involved 95 eyes from patients aged 4 to 48 years old. Among those, 65 eyes had congenital ptosis, and 30 eyes had acquired ptosis. Patients were grouped based on ptosis severity (mild, moderate, severe) and laterality (unilateral or bilateral). All participants underwent a comprehensive corneal evaluation using the MS-39 Tomographe. Parameters assessed included Kmax, thinnest pachymetry, ISV, IVA, KI, and astigmatism axis/power. Qualitative analysis examined corneal shape (symmetric/asymmetric bowtie), cone location (central/inferior), and type of astigmatism (regular/irregular). Statistical analysis was performed using IBM SPSS Statistics 23.
Results
Keratoconus-suspect topographic patterns were observed in 42% of congenital ptosis cases and 25% of acquired ptosis cases. Mean Kmax was significantly higher in the severe congenital ptosis group compared to the mild group . ISV and IVA values were elevated in congenital ptosis patients, especially in bilateral severe cases, with mean ISV reaching 56 ± 7. Asymmetric bowtie and inferior cone displacement were predominant in 64% of congenital ptosis cases versus 35% in acquired ptosis. A positive and statistically significant correlation was found between ptosis severity and the degree of corneal astigmatism.
Conclusion
Congenital ptosis, particularly in moderate to severe and bilateral forms, is associated with increased corneal irregularity, higher keratoconus indices, and greater risk of irregular astigmatism. Early corneal screening is recommended for ptosis patients to detect ectatic changes and guide early treatment and visual rehabilitation
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Sarra | Belgacem | excellence clinique ophtalmologique, optometry group, Oran university |
| Saoussane | habana | optometry group, Oran university |
| Chihab | Hadid | faculty of medecine, Annaba university |
