Is Lacrimal Gland Excision a Viable Alternative for the Treatment of Epiphora in Canalicular Obstruction?
Author: Flavia Quaranta-Leoni
Base Hospital / Institution: Ophthalmology Unit, Department of Experimental Medicine, University of Rome Tor Vergata
ePoster presentation
Abstract ID: 25-322
Purpose
To assess the effects of orbital lobe dacryoadenectomy on tear production and ocular surface health, and its potential role in treating refractory epiphora due to canalicular obstruction.
Methods
This study included 9 patients who underwent orbital lobe dacryoadenectomy: 4 with refractory epiphora due to canalicular obstruction, 3 with pleomorphic adenoma, and 2 with chronic inflammatory disease. Patients underwent either partial or complete excision of the orbital lobe. Outcome measures included Schirmer I test, ocular surface staining, and patient-reported symptoms before and after surgery. Mean follow-up was 16 +/_ 4.6 months.
Results
All patients reported improvement in epiphora. No cases of dry eye symptoms or positive ocular surface staining were observed. In the group with canalicular obstruction, epiphora relief was consistent, and no adverse effects on the ocular surface were noted.
Conclusion
Partial or complete excision of the orbital lobe of the lacrimal gland does not result in clinically significant dry eye in otherwise healthy individuals. In selected cases of canalicular obstruction, dacryoadenectomy may offer a safe and effective alternative for managing persistent epiphora when other treatments have failed or refused by the patients. Imaging findings suggest the lacrimal gland does not regenerate following excision, indicating limited or absent regenerative potential.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Serena | Panariello | Department of Translational Medicine, University of Ferrara, Ferrara, Italy |
| Francesco | Quaranta-Leoni | Oftalmoplastica Roma |
