Title: Triamcinolone Irrigation of Surgical Wound Reduces Post-Blepharoplasty Edema: A Double-Blind Randomized Controlled Trial
Author: Nasser Karimi
Base Hospital / Institution: Rassoul Akram Hospital/ Iran University of Medical Sciences
ePoster presentation
Abstract ID: 24-333
Purpose
To investigate the effect of triamcinolone irrigation in reducing postoperative inflammation after upper blepharoplasty.
Methods
This double-blind randomized controlled trial (IRCT20220424054640N1) employed balanced block randomization with 21 participants (42 eyes). One eye received triamcinolone irrigation before wound closure; the other served as a control. Pain, edema, and ecchymosis were assessed at 6 hours, 24 hours, and 72 hours after surgery. The study followed a double-blind design, with both the patient and the outcome assessor blinded to the treatment allocation. Pain was rated by patients using the Visual Analog Scale (VAS), while edema and ecchymosis were evaluated according to the Surgeon Periorbital Rating of Edema and Ecchymosis (SPREE) scale. Side effects were monitored during follow-up exams.
Results
Triamcinolone irrigation of the surgical site was associated with reduced postoperative edema 24, 48, and 72 hours after surgery (P=0.08, 0.05, and 0.00, respectively). There was no significant difference in pain score and ecchymosis level between the intervention and control eye. No adverse events were observed in either group during follow-ups.
Conclusion
Triamcinolone irrigation of the wound before suture closure is a simple, safe, and effective method to reduce postoperative edema after upper blepharoplasty and potentially other periocular surgeries.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Karo | Kamangarpour | Rassoul Akram Hospital/ Iran University of Medical Sciences |
| Sahar | Askari | Rassoul Akram Hospital/ Iran University of Medical Sciences |
| Mohsen | Kashkouli | Kentucky Lions Eye Center, University of Louisville School of Medicine |
