Abstract Listings 2024

Comparative Efficacy of Probing with or without Intubation, and/or Inferior Turbinate Fracture in Simple Congenital Nasolacrimal Duct Obstruction: A Randomized Clinical Trial

Author: Seyed Mohsen Rafizadeh
Base Hospital / Institution: Farabi Eye Hospital / Tehran University of medical Science

Rapid fire oral presentation

Abstract ID: 24-395

Purpose

To compare the success rates of probing with or without monocanalicular intubation, and/or inferior turbinate fracture in resolving simple congenital nasolacrimal duct obstruction (CNLDO)


Methods

A randomized, double-blind clinical trial was conducted on children aged 12-36 months exhibiting symptoms of epiphora and/or mucous discharge along with a positive fluorescein dye disappearance test (DDT). Patients were randomly assigned to one of the following interventions: 1) probing; 2) probing and monocanalicular intubation; 3) probing and inferior turbinate fracture; 4) probing, inferior turbinate fracture, and monocanalicular intubation. Participants were categorized into two age groups (12-24 months and 24-36 months) and assessed for resolution of CNLDO three months post-surgery. Success was defined as the absence of epiphora or mucopurulent discharge and a negative DDT


Results

Among the 201 participants, 51 underwent probing alone, 53 underwent probing with intubation, 47 underwent probing with turbinate fracture, and 50 underwent probing with turbinate fracture and intubation. No significant differences were observed in age, gender, or laterality of the disease between the groups. While there was no significant difference in success rates among interventions in both age groups, patients aged 24-36 months who underwent interventions involving intubation exhibited a significantly higher success rate compared to those without intubation (93.0% vs. 76.2%; P = 0.018). However, this difference was not observed in patients aged 12-24 months (95.7% vs. 92.9%; P = 0.551)


Conclusion

Incorporating interventions such as intubation and/or turbinate fracture alongside conventional probing does not significantly alter the success rate of simple CNLDO resolution in children aged 12-24 months. However, older patients (24-36 months) may derive greater benefits from interventions involving intubation


Additional Authors

First name Last name Base Hospital / Institution
Sahel Soltani Shahgoli Farabi Eye Hospital / Tehran University of medical Science
Amin Zand Farabi Eye Hospital / Tehran University of medical Science
Mansooreh Jamshidian Tehrani Farabi Eye Hospital / Tehran University of medical Science
Erfan Bahremani Farabi Eye Hospital / Tehran University of medical Science
Mohammad Taher Rajabi Farabi Eye Hospital / Tehran University of medical Science
Amirhossein Aghajani Farabi Eye Hospital / Tehran University of medical Science
Farabi Eye Hospital / Tehran University of medical Science

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