Treatment strategies for ocular demodex infestation
Author: Anisia-Iuliana Alexa
Base Hospital / Institution: Sfantul Spiridon Hospital, UMF ” Gr.T.Popa” Iasi
ePoster presentation
Abstract ID: 24-514
Purpose
To carry out a study to identify the parasitic etiology as a risk factor for cases of chronic blepharitis and multiple chalazions which did not have clinical resolution to at least one month of antibiotic treatment.
Methods
The study was carried out at the Spiridon Iasi Emergency Hospital Romania, the study is still ongoing, the preliminary end of their representative of patients enrolled in the study will be presented in an interval of 3 consecutive months from November 2023 to January 2024. The eligible patients were those with chronic prosterior blepharitis and multiple chalazions who followed topical treatments with antibiotic ointments, anti-inflammatories, local hygiene and systemic doxycycline. The parasitological evaluations confirmed the presence of demodex folliculorum at the skin level or through the direct microscopic evaluation of 2-3 plucked palpebral cilia, subsequently the parasitological re-evaluation was carried out monthly until negative. The 52 patients were divided into 3 groups: the 1st group received gel treatment with tea tree extract and liposomes (n=16), the second group was treated with gel and antiseptic eye wipes and the third group was treated with gel (n=6), antiseptic wipes and dermatological treatment of the skin of the face and compresses with metronidazole B 2 solution and meropenem cream (n=30).
Results
2 months after treatment, 80% of those treated with associated treatment became negative, 60% of those treated with tea tree oil gel and antiseptic wipes and 33% of those treated only with the cleansing gel. Also, the time until the negative was on average 4 months for those who exclusively used the cleaning type and those who used the type and napkins and 2 months for those who had associated with local taramentu ocular sic he dermatologically applied on face skin.
Conclusion
Ocular demodex infestation is a common but clinically underdiagnosed condition. Failure to diagnose Demodex as the primary cause of patients’ signs and symptoms can lead to ineffective treatment with antibiotics and anti-inflammatories alone, which can lead to frustration for both clinician and patient.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Ana | Picioroaga | Sfantul Spiridon Hospital, UMF ” Gr.T.Popa” Iasi |
| Roxana | Ciuntu | Sfantul Spiridon Hospital, UMF ” Gr.T.Popa” Iasi |
| Madalina | Mocanu | Sfantul Spiridon Hospital, UMF ” Gr.T.Popa” Iasi |
