Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London
(plain text version here)
Incidence of orbital exenteration: a nationwide study in France over the 2006-2017 period.
Author: ARNAUD MARTEL
ePoster Number: 204
Purpose
To assess the incidence, etiologies and characteristics of patients undergoing orbital exenteration in France between 2006 and 2017. The secondary outcome was to determine whether the use of anti-SMO targeted therapies could decrease the annual incidence of orbital exenteration in France.
Methods
A national observational cohort study was conducted in France between January 2006 and December 2017. Data was collected from the national PMSI (Programme de Médicalisation des Systèmes d’Information) database provided by the CNAM (Caisse Nationale de l’Assurance Maladie). All patients undergoing orbital exenteration over the study period in France were included.
Results
One thousand and fifty-seven patients were included. The mean annual number of orbital exenterations was 88.08 (63-117), corresponding to a mean incidence of 0.135/100,000 inhabitants/year. A male predominance was noted (n=626, 59.2%). Orbital exenteration was mainly performed in elderly patients (maximum age: 75-79 years, n=160). The etiology was available for 821 patients (77.67%): malignancies were the most common (n=755; 91.96%) followed by infectious diseases (n=16; 1.95%). Over the study period, no statistical difference in mean incidence of orbital exenteration was found (p=0.132). A subgroup analysis of patients undergoing orbital exenteration for eyelid malignancy management failed to show any decrease in mean annual number of orbital exenterations between the 2010-2013 (before vismodegib approval) and 2014-2017 (after vismodegib approval) periods (p=0.686).
Conclusion
The mean annual incidence of orbital exenteration was 0.135/100,000 inhabitants in France between 2006 and 2017. Vismodegib approval did not seem to be associated with a decrease in the number of orbital exenterations performed in France.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Jacques | LAGIER | University Hospital of Nice |
| Jerome | DELAS | University Hospital of Nice |
| Edouard | FEVRIER | University Hospital of Nice |
| Alexis | CHARLES | University Hospital of Nice |
Abstract ID: 20-106