Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London
(plain text version here)
Orbital sarcomatoid carcinoma: a rare case report
Author: Chia Ching Lin
ePoster Number: 264,00
Purpose
To report a rare case of orbital sarcomatoid carcinoma with orbital bone invasion.
Methods
Case report
Results
A 65 years-old woman presented to our department with right proptosis and hypoglobus for 2 months. Orbital CT revealed a lobulated soft tissue mass about 2.5×2.5cm in size with calcification and enhancement at the extraconal space of right orbital cavity. Surgical excision of orbital tumor removal with lateral approach was done, and pathology report showed a biphasic tumor composed of both carcinoma and sarcoma. The microscopic exam and immunohistochemistry were consistent with sarcomatoid carcinoma. Further systemic survey with bone scan showed high probability of focal orbital bone invasion and low probability of distant bone metastasis. She then underwent cyclophosphamide treatment in conjunction with radiation therapy.
Conclusion
Sarcomatoid carcinoma is a malignant mixed tumor which rarely presents in orbital region. There were only 6 cases of orbital sarcomatoid carcinoma or carcinosarcoma reported in literature so far. The diagnosis is definitely by histopathological features and immunohistochemistry. Although there is no widely accepted protocol, sarcomatoid carcinoma is generally treated aggressively, including a full resection with radiotherapy, and less often, chemotherapy. It is important to follow up regularly due to the possibility of recurrences and metastases in sarcomatoid carcinoma.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Cheng-Hsien | Chang | Kaohsiung Medical University Hospital |
| Chia-Chen | Kao | Kaohsiung Medical University Hospital |
Abstract ID: 21-165
