Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London

 

 

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MRI Evaluation of Filler Material Behavior Over Time and Post-Hyalase Injection in the Periocular Region: A Case Series

Author: Alia Issa
ePoster Number: 226,00


Purpose

This study aims to evaluate the changes in volume and thickness of filler material as observed through MRI scans and to assess the effects of Hyaluronidase injections on these parameters.


Methods

A case series of seven patients who underwent filler injections was analyzed. Each patient had 2 to 3 MRI scans taken at different intervals to monitor the filler material. The MRI intervals ranged from one to twenty-one months. These varied intervals allowed for the observation of both short-term and long-term changes in filler volume and thickness. Following the initial observations, Hyaluronidase was injected into specific filler sites at a defined unit, and subsequent MRI scans were obtained. Changes in filler volume and thickness compared to Hyaluronidase units were measured and compared across different time points pre- and post-Hyaluronidase injection.


Results

This study quantified the changes in filler volume compared to injected Hyaluronidase for the first time. Notably, areas not treated with Hyaluronidase showed no change in thickness, indicating the localised effectiveness of the treatment. These findings underscore the efficacy of Hyaluronidase in targeted filler reduction, the Units that are needed to dissolve filler, and the necessity for ongoing monitoring of untreated areas to understand the full spectrum of filler dynamics.


Conclusion

The study demonstrates that MRI is a valuable tool for monitoring the behaviour of filler materials in vivo. Hyaluronidase injections significantly accelerate the natural degradation process, providing a reliable method for correcting overfilled or misplaced filler material. These findings support the use of MRI and Hyaluronidase as effective tools in managing and correcting aesthetic filler procedures.


Additional Authors

First name Last name Base Hospital / Institution
Daniel Ezra The Ezra Clinic
Caroline Wilde The Ezra Clinic

Abstract ID: 25-389