Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London
(plain text version here)
Effect of Thyroid Hormone Status on Complete Blood Cell Count-Derived Inflammatory Biomarkers in Patients with Moderate-to-Severe Graves’ Ophthalmopathy
Author: Özge Sarıtaş
ePoster Number: 117
Purpose
To evaluate the role of abnormal thyroid function tests (TFT) on complete blood count-derived inflammatory biomarkers in patients with Graves’ ophthalmopathy (GO).
Methods
Medical records of 56 patients with inactive moderate-to-severe GO were analyzed retrospectively. Thirty-four GO patients with abnormal TFT composed Group 1 (20 F, 14 M) 22 patients who had normal TFT for at least three months composed Group 2 (14 F, 8 M). Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV) and systemic immune-inflammatory index (SII) were evaluated.
Results
The mean age was 42.3±13.0 in Group 1, 49.09±9.4 in Group 2 (p=0.06). The NLR, MLR, PLR, and SII levels were found to be higher in moderate-to-severe GO patients with abnormal TFT (p<0.05). There was no statistically significant difference in MPV levels between the two groups (p=0.91).
Conclusion
The higher levels of NLR, MLR, PLR, and SII may serve as critical findings of systemic inflammation in inactive moderate-to-severe GO patients with abnormal TFT. Therefore, the tight regulation of thyroid hormone status is vital during follow-up in patients with GO.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Nilay | Yüksel | Ophthalmology Department, Ophthalmic Plastic Surgery Service, Ankara City Hospital, |
Abstract ID: 21-177