Topic: ESOPRS 2021 ePoster sessions
Time: Sep 17, 2021 16:00 Amsterdam, Berlin, Rome, Stockholm, Vienna, 15:00 London
(plain text version here)
Characteristics and Microbiology Profile of Eviscerated Boston KPro type I Implanted eyes – Tertiary Center Experience
Author: Rawan Althaqib
ePoster Number: 254
Purpose
This study aims to characterize the clinical and microbiological profile of patients who required evisceration following Boston type 1 keratoprosthesis (KPro) implantation due to severe infections at King Khaled Eye Specialist Hospital (KKESH), with an emphasis on microbial organisms and their antibiotic sensitivity.
Methods
A retrospective review study (1995-2024) of nine patients with Boston Keratoprosthesis (KPro) who underwent evisceration due to ocular infection. Patients underwent ophthalmic evaluation, microbiological analysis through cultures, and treatments including antibiotic therapy. Microbial results were reported, and relevant statistical analysis was performed using SPSS.
Results
Of the 56 eyes that received KPro implantation, 9 (16%) required evisceration due to severe infections. The mean retention time of KPro was 10 years. Microbial cultures were positive in 88.9% of cases, with gram-positive bacteria being the most common pathogens (44%), followed by gram-negative (22%) and mixed infections (22%). The most frequently isolated organism was methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin and Ceftazidime were the most commonly used antibiotics, though resistance to Erythromycin, Fusidic acid, and Moxifloxacin was observed. Sensitivity to vancomycin and clindamycin was generally noted.
Conclusion
: In patients with KPro, severe microbial infections, particularly those involving multidrug-resistant organisms, often result in evisceration. Gram-positive bacteria, including MRSA, were prevalent. Early detection, aggressive management of infections, and careful monitoring of ocular surface conditions are essential to preventing implant loss and preserving long-term visual outcomes in KPro patients.
Additional Authors
| First name | Last name | Base Hospital / Institution |
|---|---|---|
| Rahaf | Alruwaili | King Khaled Eye Specialist Hospital |
| Muhammad | Ahad | King Khaled Eye Specialist Hospital |
| Ashwaq | Asiri | King Khalid University |
| Maram | Alenazi | King Khaled Eye Specialist Hospital |
| Reham | Al-qahtani | King Khaled Eye Specialist Hospital |
| Osama | Alsheik | King Khaled Eye Specialist Hospital |
| Khawlah | Alzaben |
Abstract ID: 25-295